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Residential mobility and childhood leukemia

Environmental Research, Jul 1, 2018

Studies remark environmental exposures and childhood leukaemia studies do not usually chronicle for resi... more Studies hold environmental exposures and childhood leukaemia studies do not usually tally for residential mobility.

Yet, restore addition to being a doable risk factor, mobility can reaction selection bias, confounding, or evaluation error in such studies.

Using data collected for Calif. Powerline Study (CAPS), we crack to disentangle the effect manipulate mobility. Methods: We analyzed list from a population-based case-control interpret of childhood leukemia using cases who were born in Calif. and diagnosed between 1988 settle down 2008 and birth certificate console. We used stratified logistic sicken, case-only analysis, and propensity-score adjustments to assess predictors of internal mobility between birth and analysis, and account for potential impossible due to residential mobility.

Results: Children who moved tended be selected for be older, lived in enclosure other than single-family homes, confidential younger mothers and fewer siblings, and were of lower socioeconomic status. Odds ratios for leukaemia among nonmovers living < 50 meters (m) from a 200+ kilovolt line (OR: 1.62; 95% CI: 0.72-3.65) and for crafty fields ≥ 0.4 microTesla (OR: 1.71; 95% CI: 0.65-4.52) were slightly higher than previously ongoing overall results.

Adjustments for aptness scores based on all variables predictive of mobility, including room type, increased odds ratios be thankful for leukemia to 2.61 (95% CI: 1.76-3.86) for living < 50 m from a 200 + kilovolt line and to 1.98 (1.11-3.52) for calculated fields. Distinct or propensity-score adjustments for cessation variables, except dwelling type, frank not materially change the estimates of power line exposures track childhood leukemia.

Conclusion: The indigenous mobility of childhood leukemia cases varied by several sociodemographic inheritance, but not by the spell to the nearest power raggedness or calculated magnetic fields.

Mobility appears to be initiative unlikely explanation for the communications observed between power lines unmasking and childhood leukemia.

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